RQ-PCR analysis of Ig/TCR gene rearrangements for quantitative MRD diagnostics in lymphoid malignancies such as ALL or NHL is a highly complex technology which needs extensive knowledge and experience. To become a participant of EuroMRD, an MRD-PCR laboratory needs to meet several requirements, including:
- Extensive knowledge of IG/TCR gene rearrangements;
- Extensive experience with MRD detection via IG/TCR gene rearrangements or other patient-specific PCR targets at the DNA level;
- Position of MRD laboratory: size (personnel), relation to (inter)national treatment protocols, and minimum annual intake of new patients.
Every two years, the status of the EuroMRD participantship is evaluated.
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