Guidelines for RQ-PCR MRD

The EuroMRD guidelines for interpretation of real-time quantitative (RQ) PCR data for analysis of minimal residual disease based on Ig/TCR gene rearrangements can be downloaded below:

Updated guidelines 2024: Van der Velden et al., Leukemia 2024;38:1315-22: Analysis of measurable residual disease by IG/TR gene rearrangements: quality assurance and updated EuroMRD guidelines

Kotrova et al., Leukemia 2024;38:1617-20: The gray area of RQ-PCR-based measurable residual disease: subdividing the “positive, below quantitative range” category

Guidelines 2007: Van der Velden et al., Leukemia 2007;21:604-11: Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data